Multiple Myeloma Causes

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7 hours ago Scientists still do not know exactly what causes most cases of multiple myeloma. However, they have made progress in understanding how certain changes in DNA can make plasma cells become cancerous. DNA is the chemical that carries the instructions for nearly everything our cells do. Some genes (parts of our DNA) contain instructions for

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8 hours ago Kelly Crumrin. Like all cancers, multiple myeloma is caused by genetic mutations that allow cells to divide and grow in a disorganized way. Normal cells divide in a regular, ordered fashion, forming new cells that are exact copies to replace old cells. Certain genes in each cell are responsible for telling cells when to start dividing.

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5 hours ago Prevention. For some types of cancer, risk factors are known for the majority of cases. For example, smoking causes most lung cancers. This provides an opportunity for prevention. With multiple myeloma, few cases are linked to risk factors that can be avoided, so there is no known way to prevent most multiple myelomas from developing.

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2 hours ago Occupation, Exposure to Chemicals, Sensitizing Agents, and Risk of Multiple Myeloma in Sweden. 8. Radiation. People who are exposed to high levels of radiation are more likely to develop myeloma. Read more: S Wing, D Richardson, S Wolf, G Mihlan, D Crawford-Brown, & J Wood (2000).

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4 hours ago Multiple myeloma is the second most common type of blood cancer after leukemia. Learn more about the symptoms, causes, diagnosis, risk factors, and treatment of multiple myeloma.

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5 hours ago The exact underlying cause of Multiple myeloma is currently unknown. Factors that are associated with an increased risk of developing Multiple myeloma include increasing age, male sex, African American race, radiation exposure, a family history of the condition, obesity, and/or a personal history of monoclonal gammopathy of undetermined

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4 hours ago Myeloma, also called multiple myeloma, is a cancer of the plasma cells. In myeloma, the cells grow too much, crowding out normal cells in the bone marrow that make red blood cells, platelets, and other white blood cells. What Causes Myeloma? Scientists don’t understand why some people get myeloma and others don’t. Age is the most

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5 hours ago Nonetheless, the increasing life expectancy of the MM population might translate into an increase in causes of death (COD) unrelated to MM…”. The most common causes of death for multiple myeloma survivors are: Myelosuppression (Infection, pneumonia, etc,) Renal Insufficiency (kidney failure) Bone Disease (bone damage, fractures, leading to

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6 hours ago Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, kidney dysfunction, and infections may occur. Complications may include amyloidosis.. The cause of multiple myeloma is unknown.

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Just Now Multiple Myeloma Causes. Multiple myeloma causes are largely unknown. Through extensive research, scientists have learned that this form of cancer develops when plasma cells in the bone marrow mutate and become malignant. As a result of genetic mutations, the unhealthy cells grow and divide at a very rapid pace and don’t die when they

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9 hours ago Myeloma is a cancer of certain white blood cells (WBC) in the bone marrow called plasma cells that are responsible for making antibodies (immunoglobulins). A malignant (cancerous) plasma cell is called a myeloma cell. In this section, you will learn more about multiple myeloma's symptoms and causes.

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6 hours ago There are also thought to be multiple environmental factors which may increase the risk of developing myeloma. These include exposure to certain types of industrial and agricultural chemicals, exposure to high doses of radiation, viruses and a weakened immune system. However, in the majority of cases, the causes of myeloma are likely to be

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1 hours ago The pain can be mild or severe depending on the extent of the multiple myeloma, the speed with which it has developed, and whether fracture or nerve compression has occurred. Fatigue and/or shortness of breath: Myeloma can cause anemia, which can lead to feeling short of breath with exertion or tiredness more than usual.

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5 hours ago Multiple myeloma is a type of cancer affecting the plasma cells, which are a type of white blood cell. It can cause mental confusion in some people. Multiple myeloma (MM) alters the way a person

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Just Now The exact cause of multiple myeloma is unknown. However, it starts with one atypical plasma cell that rapidly multiplies in the bone marrow. The resulting cancerous myeloma cells don’t have a

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2 hours ago Multiple myeloma is a type of blood cancer. Read about the basics of the disease, including what causes it, how it makes you feel, stages of the disease, and other important facts you need to …

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3 hours ago 1. Introduction. Multiple myeloma (MM) is a rare blood disease, representing 1% of cancers and 10% of all hematological malignancies, being the second most common blood cancer [1,2].MM is frequently associated with the elderly, as the majority of the patients are diagnosed between the age of 60 and 70; however, in recent years younger patients have …

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Frequently Asked Questions

What are the main causes of multiple myeloma?

What are the main leading causes of multiple myeloma?

  • Age. Myeloma occurs most commonly in people over 60. ...
  • Race. Myeloma occurs twice as frequently in Black people than in white people. ...
  • Exposure to radiation or chemicals. ...
  • Personal history. ...
  • Monoclonal gammopathy of undetermined significance (MGUS). ...
  • Gender.

What are my chances of getting multiple myeloma?

Stage I: All of the following apply:

  • β2-M less than 3.5 mg/L
  • Serum albumin of 3.5 g/dL or more
  • Normal LDH
  • No high-risk chromosome changes in myeloma cells found by FISH test

What are the signs and symptoms of multiple myeloma?

Symptoms - Multiple myeloma

  • Bone pain. Multiple myeloma can cause pain in affected bones – usually the back, ribs or hips. ...
  • Bone fractures and spinal cord compression. Multiple myeloma can weaken the bones and make them more likely to break (fracture). ...
  • Anaemia. ...
  • Repeated infections. ...
  • Raised calcium levels in the blood. ...
  • Unusual bleeding. ...
  • Thickened blood. ...
  • Kidney problems. ...

Is multiple myeloma a fatal disease?

The integration of novel agents into the treatment paradigm has shifted the perception of multiple myeloma (MM) from an incurable, fatal disease to a manageable, chronic one. This comprehensive review addresses the results and challenges posed by many of the newer agents for the treatment of RRMM.

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