Sickle Cell Disease

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2 hours ago Sickle cell disease is a group of inherited red blood cell disorders that affects hemoglobin, the protein that carries oxygen through the body. The condition affects more than 100,000 people in the United States and 20 million people worldwide. Normally, red blood cells are disc shaped and flexible to move easily through the blood vessels.

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8 hours ago Sickle cell disease (SCD) is a group of inherited red blood cell disorders. In SCD, the red blood cells become hard and sticky and look like a C-shaped farm tool called a “sickle.” People with SCD can live full lives and enjoy most of the activities that other people do. If you have SCD, it’s important to learn how to stay as healthy as possible.

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4 hours ago Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease. It affects the shape of red blood cells, which carry oxygen to all parts of the body. Red blood cells are usually round and flexible, so they move easily through blood vessels. In sickle cell anemia, some red blood cells are shaped like sickles or crescent

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Just Now Sickle cell disease is caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. Hemoglobin transports oxygen from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) …

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2 hours ago Sickle cell disease is an inherited blood disorder marked by defective hemoglobin. It inhibits the ability of hemoglobin in red blood cells to carry oxygen. Sickle cells tend to stick together, blocking small blood vessels causing painful and damaging complications. Sickle cell disease is treated with pain medications as needed, drinking 8 to

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2 hours ago Sickle cell disease is an inherited disorder that affects your red blood cells, producing a negative impact on your health. In SCD, your hemoglobin is not normal and cannot pass easily through your blood vessels. Hemoglobin is a protein that is part of your red blood cells. It is the substance that carries oxygen in the blood.

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6 hours ago Sickle cell disease is an inherited blood disorder affecting red blood cells. Normal red blood cells contain hemoglobin A. People with sickle cell disease have red blood cells containing mostly hemoglobin S, an abnormal type of hemoglobin. These red blood cells become sickle-shaped (crescent-shaped), and have difficulty passing through small

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9 hours ago Sickle cell disease is a group of inherited disorders. The specific type of SCD a person has depends on which HBB gene mutations they inherited from their parents. The HBB gene gives instructions for a part of hemoglobin, which is the protein that travels through the blood to deliver oxygen throughout the body. 1.

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4 hours ago Sickle cell disease around the world. There is no reliable estimate of global SCD cases. However, about 300,000 babies are born every year with sickle cell anemia. Most of these cases occur in Nigeria, the Democratic Republic of the Congo, and India. 2. Experts predict this number will pass 400,000 by 2050.

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5 hours ago Sickle cell disease (SCD) is a multisystem disorder and the most common genetic disease in the United States, affecting 1 in 500 African Americans. About 1 in 12 African Americans carry the autosomal recessive mutation, and approximately 300,000 infants are born with sickle cell anemia annually. The understanding of the phenotypic expression of the …

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1 hours ago Sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell disease have red blood cells that contain mostly hemoglobin S, an abnormal type of hemoglobin. Sometimes these red blood cells become sickle-shaped (crescent shaped) and have difficulty passing through small blood vessels.

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3 hours ago Sickle cell disease is an inherited blood disorder that can cause anemia, severe pain, infections, organ damage, and stroke. It is a lifelong condition that …

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1 hours ago Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB, which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 and 400,000 neonates globally each year, the majority in sub-Saharan Africa. Haemoglobin molecules that include mutant sickle

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3 hours ago Abstract. Blood transfusion remains an important therapeutic intervention in patients with sickle cell disease (SCD), aiming to both increase the oxygen carrying capacity of blood and to reduce the complications of vaso-occlusion. Simple, manual exchange and automated exchange can be effective in reducing the acute and chronic complications of

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6 hours ago Sickle cell disease (SCD) is a group of inherited red blood cell disorders. If you have SCD, there is a problem with your hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. With SCD, the hemoglobin forms into stiff rods within the red blood cells. This changes the shape of the red blood cells.

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3 hours ago Sickle Cell Disease Causes and Risk Factors. Sickle cell disease is caused by a problem in the hemoglobin-beta gene found on chromosome 11. The defect forms abnormal hemoglobin.

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5 hours ago Sickle cell disease is the most common inherited blood disorder in the United States, affecting about 100,000 Americans. It can occur in all races but is most common in African-Americans and Hispanics. About one out of 365 African-American babies born in the US has sickle cell disease.

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What you should know about sickle cell disease?

• Sickle cell disease makes red blood cells stick together and get stuck in blood vessels. This can cause pain, blood clots, and problems with organs including the heart, lungs, and kidneys. 1, 2 • Having sickle cell disease also makes it easier to get infections. • People who have sickle cell disease are born with it. It is estimated that 100,000 Americans have this disease. 4

What is sickle cell disease is caused by?

Sickle cell is a progressive and unpredictable genetic disease caused by a change (mutation) in both copies of the HBB gene that you inherit from your parents. This change affects the hemoglobin protein, which causes people with sickle cell to produce an abnormal form of hemoglobin called hemoglobin Sickle (HbS).

What are facts about sickle cell disease?

  • Sickle cell disease is the most common genetic blood disorder. ...
  • It affects many races, not just African Americans. ...
  • Hemoglobin SS is the most common type of sickle cell disease. ...
  • Specialized blood tests (Hemoglobin Electrophoresis and a CBC) are needed to confirm whether or not you have sickle cell trait or sickle cell disease. ...

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How does sickle cell disease affect the body?

• Sickle cells can get stuck in small blood vessels and block the flow of blood and oxygen to organs in the body. These blockages cause repeated episodes of severe pain, organ damage, serious infections, or even stroke.

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